WebMar 20, 2024 · We further identified natriuretic peptide clearance receptor Npr3, a beige fat repressor, as a marker gene for a subset of white adipocytes and an aging-upregulated gene in adipocytes. In summary, this study indicates that aging blocks beige adipogenesis and dysregulates adipocyte responses to cold exposure and provides a unique resource … WebAdipogenesis and metabolic health Obesity is characterized by increased adipose tissue mass and has been associated with a strong predisposition towards metabolic diseases …
Discovery and functional assessment of a novel adipocyte ... - eLife
WebJun 16, 2024 · Adipogenesis: A Complex Interplay of Multiple Molecular Determinants and Pathways. The formation of adipocytes during embryogenesis has been largely … WebApr 12, 2024 · Recognizing the dynamic role of the adipose tissue and its contribution to a variety of physiological and pathological processes, Adipocyte explores the link between dysfunctional adipose tissue and a growing number of chronic diseases, including diabetes, hypertension, cardiovascular disease and cancer. papato di francesco
Control of Adipogenesis by the SUMO-Specific Protease SENP2
WebOct 1, 2024 · Pdgfrb-expressing adipocyte precursors undergo adipogenesis in response to HFD feeding (gonadal and retroperitoneal depots), cold exposure (inguinal beige adipocytes), and treatment with PPAR-activating thiazolidinediones (TZDs) (inguinal and gonadal depots) (62, 65). All together, these data highlight the presence of depot- and … WebAdipogenesis is a complex process whereby the multipotent adipose-derived stem cell is converted to a preadipocyte before terminal differentiation into the mature adipocyte. … WebFeb 13, 2014 · The FABP4-null preadipocytes exhibited a remarkably enhanced adipogenesis compared with wild-type cells, indicating that FABP4 regulates adipogenesis by downregulating PPARγ. We found that the FABP4 level was higher and PPARγ level was lower in human visceral fat and mouse epididymal fat compared with their subcutaneous fat. papato di avignone