Cilastatin molecular weight

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WebOct 6, 2024 · It is an off-white to yellowish-white, hygroscopic, amorphous compound with a molecular weight of 380.43. It is very soluble in water and in methanol. Its empirical formula is C 16 H 25 N 2 O 5 SNa, and its structural formula is: Imipenem and Cilastatin for Injection, USP (I.V.) is buffered to provide solutions in the pH range of 6.5 to 8.5. WebCilastatin UNII 141A6AMN38 Molecular formula C 16 H 26 N 2 O 5 S Molecular weight 358.45 Percent composition C 53.61%, H 7.31%, N 7.82%, O 22.32%, S 8.94% …

Cilastatin The Merck Index Online

WebCilastatin Molecular Formula CHNOS Average mass 358.453 Da Monoisotopic mass 358.156250 Da ChemSpider ID 4940183 - Double-bond stereo - 2 of 2 defined stereocentres More details: Featured data source … WebJan 13, 2024 · Cilastatin ammonium salt CAS Number: 877674-82-3: Molecular Weight: 375.48: Density: N/A: Boiling Point: N/A: Molecular Formula: C 16 H 29 N 3 O 5 S: … northern lights 1997

Cilastatin sodium C16H25N2NaO5S - PubChem

WebThe mean serum half-life of imipenem is about 2 hours, whereas that of cilastatin is 5 to 6.4 hours [488]. The half-life for both drugs is inversely related to birth weight and … WebJan 12, 2024 · Additionally, body weight loss due to cisplatin was not affected by cilastatin (supplementary Fig. 1C). Figure 1 Administration of cilastatin suppressed cisplatin-induced kidney injury. WebAdditional Names: Cilastatin sodium Molecular Formula: C16H25N2NaO5S Molecular Weight: 380.43 Percent Composition: C 50.51%, H 6.62%, N 7.36%, Na 6.04%, O 21.03%, S 8.43% Properties: Off-white to yellowish-white hygroscopic, amorphous solid. pKa1 2.0; pKa2 4.4; pKa3 9.2. Very sol in water, methanol. pKa: pKa1 2.0; pKa2 4.4; pKa3 9.2 how to rotate awd tires

Imipenem and Cilastatin Injection: PI - Drugs.com

Cilastatin The Merck Index Online - Royal Society of Chemistry

WebApr 15, 2024 · Her treatment with unspecified low molecular weight heparin was discontinued and she started receiving treatment with acenocoumarol. Within the third … northern lights 16kw generatorWebShowing 1-6 of 6 results for "cilastatin" within Products. Products Genes Papers Technical Documents Site Content Chromatograms. Filter & Sort. All Photos (1) Cilastatin sodium salt. ... Molecular Weight: 358.45. Compare Product No. Description SDS Pricing; SML1283: 50 mg/mL in DMSO/H 2 O, 1:1: Expand. Hide. how to rotate background image in teams

"WebMolecular Formula C13H20ClNO3 Molecular Weight 273.76 Catalogue Number AR-C02770 Parent Drug CILASTATIN CAS Number 877674-77-6 Cilastatin Ammonium Salt Synonym ammonium (Z)-7-(((R)-2-amino-2-carboxyethyl)thio)-2-((S)-2,2-dimethylcyclopropanecarboxamido)hept-2-enoate Molecular Formula C16H25N2O5S . … " - Cilastatin molecular weight

Cilastatin molecular weight

Primaxin I.V. (Imipenem and Cilastatin for Injection): Uses, …

WebCombination of imipenem and cilastatin that is used in the treatment of bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent. ... Molecular Formula. C12-H17-N3-O4-S.C16-H26-N2-O5-S. Molecular Weight. 657.8057 ... WebAug 3, 2024 · It is an off-white, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is C 12 H 17 N 3 O 4 S•H 2 O, ... Cilastatin sodium was given intravenously to rabbits at doses up to 300 mg/kg/day and to rats subcutaneously at …

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Webwhite, nonhygroscopic crystalline compound with a molecular weight of 317.37. It is sparingly soluble in water and slightly soluble in methanol. Its empirical formula is … Web199 rows · Aug 29, 2007 · The total clearance of imipenem is 0.2 L/h/kg. 8 When used alone, the renal clearance is 0.05 L/h/kg. In combination with cilastatin the renal …

WebMolecular Formula: C 16 H 25 N 2 O 5 S. Na. Molecular Weight: 357.45 22.99. Download SDS. Download COA. Related Product. C-136001. ... C-136002. Cilastatin EP Impurity C. C 22 H 36 N 2 O 6 S. M.W. 456.61. C-136003. Cilastatin. CAS No. 82009-34-5. C 16 H 26 N 2 O 3 S. M.W. 358.45. C-136004. Cilastatin EP Impurity A HCl (Mixture of … http://editor.fresenius-kabi.us/PIs/US-PH-Imipenem-and-Cilastatin-for-Inj-USP-FK-451205C-05-2015-PI.pdf

WebCilastatin sodium, Tocris Bioscience™ Structure Search; Print Cilastatin sodium, Tocris Bioscience™ Click to view available options ... Molecular Weight (g/mol) 380.435: InChI Key: QXPBTTUOVWMPJN … WebSep 4, 2024 · Cilastatin 81129-83-1 TWA 5 mg/m3 (OEB 1) Internal Imipenem 74431-23-5 TWA 1000 ug/m3 (OEB 1) Internal Further information: RSEN ... Molecular weight : No data available Particle size : No data available SECTION 10. STABILITY AND REACTIVITY

WebApr 15, 2024 · Her blood tests revealed mild inflammatory syndrome, moderate normochromic normocytic anaemia and anaemic syndrome with a hemoglobin level of 8.1 g/dL, mild thrombocytopenia with a platelet count of 121000 /µL, and subtherapeutic INR of 1.21. Based on the findings of urine analysis, she was diagnosed with a urinary tract …

WebMolecular Formula: C16H26N2O5S Molecular Weight: 358.45 Percent Composition: C 53.61%, H 7.31%, N 7.82%, O 22.32%, S 8.95% Literature References: Prevents renal … northern lights 2020 pathWeb2 days ago · Journal of Molecular Structure. Available online 12 ... (0.05 M, pH 4.5) at a dose of 100 mg/kg body weight was given to treated rats. A glucometer was used to monitor blood glucose levels one week after the STZ injection. ... Dual drug delivery of vancomycin and imipenem/cilastatin by coaxial nanofibers for treatment of diabetic foot ulcer ... northern lights 2020 predictionWebJan 10, 2024 · MOLECULAR FORMULA : C16-H26-N2-O5-S MOLECULAR WEIGHT : 358.50 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - … how to rotate background images windows 10WebThe following data is based on the product molecular weight 358.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which … northern lights 27 febWebCilastatin Ammonium Salt. Synonyms: CAS#: 877674-82-3. Alternate CAS#: Molecular Formula: C16H25N2O5S. NH4. Molecular Weight: 357.45 18.04. Download COA. Related Product. C-136001. Cilastatin EP Impurity B (Mixture of Diastereomers) C 21 H 34 N 2 O 6 S. M.W. 442.57. C-136002. Cilastatin EP Impurity C. C 22 H 36 N 2 O 6 S. how to rotate blocks in minecraftWebFeb 28, 2024 · Cilastatin was administered subcutaneously to rats (GD 6 to 17) and intravenously to rabbits (GD 6 to 18) at doses up to 1000 and 300 mg/kg/day, respectively, approximately 3.2 and 1.9 times the RHD (based on body surface area). ... It is an off-white to yellowish-white, hygroscopic, amorphous compound with a molecular weight of … northern lights 2023 ukWebA method for providing a passivation layer or pH protective coating on a substrate surface by PECVD is provided, the method comprising generating a plasma from a gaseous reactant comprising polymerizing gases. The lubricity, passivation, pH protective, hydrophobicity, and/or barrier properties of the passivation layer or pH protective coating are set by … northern lights 2011