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Crystalluria acyclovir

WebOf 19 children treated with high-dose intravenous acyclovir, 7, all of whom had encephalitis, also had a restricted fluid intake. Of these, 3 experienced nonoliguric renal insufficiency (plasma creatinine up to 176, 250 and 351 μmol/l, respectively) which resolved within 1 week of discontinuing acyclovir. Renal function was stable in the remaining 4 patients in … WebApr 1, 2008 · One of the mechanisms for acyclovir-induced nephrotoxicity is acyclovir-induced crystalluria. Prompt attention to urine microscopy examination can help avoid drug-induced nephrotoxicity.

Acute renal failure related to topical acyclovir - Clinical Advisor

WebNov 14, 2024 · Acyclovir is one of the most common prescribed antiviral drugs. Acyclovir nephrotoxicity occurs in approximately 12–48% of cases. It can present in clinical … WebJun 2, 2024 · Laboratory staff should be aware and recognize acyclovir treatment as a possible cause of pathologic crystalluria. Any case of moderate to abundant … chit chat city 2 https://videotimesas.com

Acyclovir Side Effects: Common, Severe, Long Term - Drugs.com

WebJan 1, 2016 · Acyclovir is a highly active antiviral drug that acts against the herpes simplex virus (HSV). Among its secondary effects, we can observe rare cases of crystalluria, which can be associated or not ... WebJul 8, 2009 · The crystalluria was accompanied by impairment of the renal tubules as evidenced by increased urinary beta-2-microglobulin excretion. Consecutive series of 60 … WebCrystalluria is usually clinically insignificant, but can be important in limited situations. Crystal type is important in association with current or prior occurrence of calculi and when one suspects a portosystemic shunt, ethylene glycol toxicity (Figure 7-7 ), or melamine intoxication. Whenever crystalluria is considered significant, it is ... graph with arrow going up

Acyclovir Nephrotoxicity: A Case Report …

Category:Mechanisms of antimicrobial-induced nephrotoxicity in children

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Crystalluria acyclovir

National Center for Biotechnology Information

WebJun 2, 2024 · Intravenous acyclovir administration may result in a pathologic crystalluria, especially in cases with increased renal concentration of the drug. It is important that clinical laboratory staff... Webcrystalluria: [ kris″tah-lu´re-ah ] the excretion of crystals in the urine, causing irritation of the kidney.

Crystalluria acyclovir

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WebApr 19, 2024 · Acyclovir is an antiviral drug that slows the growth and spread of the herpes virus in the body. It may be used to treat herpes infections such as: Chickenpox; Cold … WebFor decades, acyclovir-induced nephrotoxicity was believed to be secondary to crystalluria. Clinical evidence of nephrotoxicity in the absence of crystalluria suggests that acyclovir …

WebMar 6, 2024 · Applies to acyclovir: buccal tablet, compounding powder, intravenous powder for injection, intravenous solution, oral capsule, oral suspension, oral tablet. General The …

WebAcyclovir crystalluria is a rare condition which is generally described in immunosuppressed adult patients. It can lead to transient renal failure, and therefore it shall be taken into … WebAcyclovir crystalluria is considered a rare adverse effect which is more commonly described if there is intravenous administration. However, it may also be associated with oral administration [9]. It is more common in immunosuppressed patients, probably due …

WebJul 8, 2009 · Acyclovir crystals in the urine of a 28-year-old woman are described. The patient received intravenous acyclovir for herpes encephalitis. The crystalluria was accompanied by impairment of the renal tubules as evidenced by increased urinary beta-2-microglobulin excretion. Consecutive series of 60 patients on oral acyclovir and 20 …

WebNational Center for Biotechnology Information graph with a slope of -1/4WebAcyclovir is filtered by glomeruli and secreted in renal tubules producing high tubular concentrations. It is relatively insoluble in urine. Intra-tubular crystals obstruct the nephron leading to acute renal failure. Crystalluria usually … graph with a point and slopeWebJul 1, 2002 · The acyclovir can cause crystalluria though it is an uncommon side effect of commonly used drugs. [7] The occurrence of acyclovir-induced crystalluria increases when high dosages are given... chit chat city go to a certain shopWebAcyclovir crystals may precipitate in the renal tubules, particularly when the drug is injected intravenously as a bolus. Abnormal renal function may occur, which is usually reversible but may infrequently progress to tubular damage and acute renal failure. graph with a slope of 3/2WebJul 15, 2012 · Drug-induced nephrotoxicity appears to be attributed to renal tubular damage caused by acyclovir-induced crystalluria (Pathol Lab Med. 2002;126:753-754). Topical acyclovir is available by ... chit chat city homesWebAcyclovir is widely used to treat herpes virus infections, particularly those associated with herpes simplex virus and varicella-zoster virus. Randomized controlled trials have shown that acyclovir effectively reduces the duration and severity of painful lesions, prevents complications, and decreases recurrence . chit chat city onlineWebJun 1, 1988 · One patient was rechallenged with low-dose intravenous acyclovir and the four patients later received oral acyclovir, all without adverse effect. The combined data from these patients support crystalluria and obstructive nephropathy as a mechanism of acyclovir-induced renal failure in humans. graph with a period of 2pi