WebThe functional alteration in forkhead box L2 transcription factor (FOXL2) is responsible for this syndrome. FOXL2 was mapped on chromosome 2q23. To date, more than 270 FOXL2 variants have been reported [91]. Depending on the functional alteration the mutation produces on the protein, the phenotype may vary [92,93]. WebAn intronless gene on chromosome 9q22 that encodes a member of the forkhead family of transcription factors, specifically a thyroid transcription factor, which plays a crucial role …
Examination of the role of the forkhead box L2 (Foxl2) in gonadal …
WebRecombinant Anti-FOXL2 antibody [EPR23523-68] (ab246511) Datasheet SDS Certificate of Compliance Reviews ( 3) Submit a question References (2) +7 Key features and details Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply Rabbit monoclonal [EPR23523-68] to FOXL2 WebFOX (forkhead box) proteins are a family of transcription factors that play important roles in regulating the expression of genes involved in cell growth, proliferation, differentiation, and longevity. Many FOX proteins are important to embryonic development. if your cat is not eating
FOXL2 - Wikipedia
WebForkhead box protein L2 is a protein encoded by the FOXL2 gene in humans. The gene FOXL2 encodes a member of the fork-head-winged-helix family of transcription factors. It is expressed early during female gonadal development and is expressed in normal ovarian stroma and ovarian neoplasms with granulosa cell lineage. [ 2] FOXL2 is involved in sex determination. FOXL2 knockout in mature mouse ovaries appears to cause the ovary's somatic cells to transdifferentiate to the equivalent cell types ordinarily found in the testes. Polled Intersex Syndrome in goats is caused by a biallelic loss-of-function in FOXL2 transcription and leads to in utero female-to-male sex-reversal. Several SNPs (Single Variant Polymorphisms) in the genomic region 3q23 overlapping the fork… WebJul 9, 2024 · PMCID: PMC7347172. DOI: 10.1371/journal.pone.0234795. Abstract. Forkhead box L2 (FOXL2) is a single-exon gene encoding a forkhead transcription … istd ucas