Fstl1 macrophage
WebMay 17, 2014 · Follistatin-like protein 1 (FSTL1), a secreted glycoprotein, also named TSC-36 [transforming growth factor (TGF)β 1-stimulated clone 36] or FRP (follistatin-related protein), was originally cloned from the mouse osteoblastic cell line MC3T3-E1 [].FSTL1 is widely expressed in human and mouse tissues, although its expression was found to be … WebDec 1, 2024 · FSTL1 is reported to induce the release of macrophages- and fibroblasts-derived inflammatory cytokines [14], demonstrating that FSTL1 plays a pro-inflammatory role. Zhang et al. found that miR-32-5p facilitates the survival of M.tb pathogen and restrains the release of inflammatory factors in macrophages, and FSTL1 overexpression …
Fstl1 macrophage
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WebCardiovascular diseases [ edit] FSTL1 protein seems to have a cardioprotective role. FSTL1 attenuated hypertrophy following pressure overload [17] and prevented myocardial ischemia/reperfusion injury in a mouse or pig model of ischemia/reperfusion. [18] Muscle-derived Fstl1 modulates vascular remodelling in response to injury. WebApr 12, 2024 · Follistatin-like protein 1 (Fstl1), a glycoprotein widely expressed in human and mouse tissues, is a tumor suppressor in various cancers and a regulator in …
WebAug 5, 2024 · An MSC-macrophage co-culture system was constructed to further confirm the role of FSTL1 in the immunosuppressive capacity of MSCs. RNA sequencing was … WebMay 1, 2014 · Myeloid-specific FSTL1-knockout (FSTL1 M-KO ) mice were constructed to explore the function and mechanism of macrophage FSTL1 in 3 murine models of liver fibrosis induced by carbon tetrachloride ...
WebMay 12, 2024 · These results showed that circ-WDR27 repressed M.tb vitality and stimulated pro-inflammatory cytokines in M.tb-infected macrophages by affecting the miR-370-3p/FSTL1 axis. Tuberculosis (TB) is a common disease caused by Mycobacterium tuberculosis (M.tb) infection. Our study was to explore the function and mechanism of … WebMar 29, 2024 · Follistatin-like 1 (FSTL1) is a secreted glycoprotein displaying expression changes during development and disease, among which cardiovascular disease, cancer, …
WebWhile cells of mesenchymal lineage are capable of FSTL1 production, FSTL1 expression is notably absent from cells of hematopoietic lineage under normal physiological conditions. Macrophages and monocytes are, however, capable of taking up FSTL1 at sites of inflammation where FSTL1 stimulation can cause the expression of caspase-1 and its ...
WebObjective Follistatin-like protein 1 (FSTL1) is widely recognised as a secreted glycoprotein, but its role in modulating macrophage-related inflammation during liver fibrosis has not been documented. Herein, we … horsham bearings horshamWeb联系我们 Contact Us. 电话：400-188-1050 邮箱：[email protected] pss mof go krWebFeb 17, 2012 · Follistatin-related protein (FRP)/follistatin-like 1 (FSTL1) is a secreted glycoprotein and a member of the follistatin protein family. FRP binds transforming growth factor β (TGF-β ... endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression. J. Immunol., 164 (2000 ... horsham bedding centre saleWebJun 1, 2024 · In addition, transfection of FSTL1 into cultured fibroblasts and macrophages upregulated production of pro-inflammatory cytokines, including IL-1β, TNF-α, and IL-6 [50]. Moreover, Clutter and his colleagues injected adenovirus to facilitate FSTL1 overexpression in vivo, causing significant swelling of the paws and upregulation of CXCL10 and ... pss motorized lensWebObjective: Asthma, a well-known disease with high morbidity, is characterized by chronic airway inflammation. However, the allergic inflammation mechanisms of follistatin-like … horsham bedding centre horshamWebCD51 + CD61 (Integrin alpha V + Integrin beta 3) CD51 / Integrin alpha V. CD52 horsham bed centreWebFeb 9, 2024 · Objective Follistatin-like protein 1 (FSTL1) is widely recognised as a secreted glycoprotein, but its role in modulating macrophage-related inflammation during liver … horsham bed and breakfast