Griffithsin patent
WebPatent Application No. 63/026,375 described above, as well as a second U.S. Provisional Patent Application No. 63/070,375 entitled “Q-Griffithsin Nasal Spray,” (HHS Ref. No. E-029-2024-1-US-01), filed on August 26, 2024. The Government of the United States is not a co-owner on this second US Provisional Patent Application, and it is therefore, WebThe results show that griffithsin is potently active (sub-nanomolar EC 50 values) against a broad range of HIV isolates including T-tropic viruses (utilizing CCR5 as a co-receptor) and M-tropic viruses (utilizing CXCR4 as a co-receptor). This picomolar level of activity is more potent than that described for most of the current anti-HIV agents utilized in therapy or in …
Griffithsin patent
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WebNov 16, 2024 · Detailed Description: Q-Griffithsin (Q-GRFT) nasal spray is an investigational product that has broad spectrum antiviral activity. Q-GRFT is derived from … Webgriffithsin viral virus polypeptide hiv Prior art date 2004-06-01 Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal …
WebInterPro. Griffithsin is a protein isolated from the red algae Griffithsia. It has a 121- amino acid sequence [2] which exhibits a Jacalin-like lectin fold. Several structures of this … WebNov 4, 2024 · Griffithsin (GRFT) is a high-mannose oligosaccharide-binding lectin currently being evaluated in phase I clinical trials as a topical microbicide for the prevention of human immunodeficiency virus (HIV-1) …
WebJul 24, 2024 · Griffithsin is a marine algal lectin that exhibits broad-spectrum antiviral activity by binding oligomannose glycans on viral envelope glycoproteins, including those found in HIV-1, HSV-2, SARS, HCV and other enveloped viruses. Webgriffithsin cov sars protein infection Prior art date 2024-08-24 Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Pending Application number CN202410867243.0A Other languages English (en) Inventor ...
WebAug 10, 2010 · U.S. Provisional Patent Application Serial No. 60/741.403, filed on Start Printed Page 48356 December 1, 2005, ... Griffithsin is a novel, potent anti-HIV protein … new directions intakeWebJul 8, 2024 · The patent rights for this technology cover the sequence of the GRFT polypeptide as well as several GRFT variants mutated to render them glycosylation … new directions intercare south hillsWebGriffithsin, a Highly Potent Broad-Spectrum Antiviral Lectin from Red ... new directions in thermoresponsive polymersWebFeb 10, 2016 · The invention provides modified griffithsin polypeptides comprising the amino acid sequence of SEQ ID NO: 1, as well as corresponding nucleic acids, vectors, cells, … new directions intercareWebparticular molecule carries no net electrical charge) of the modified griffithsin polypeptides can optimize the bioavailability of the modified griffithsin polypeptides in different compartments of the body (e.g., nasal cavity, lung, gut, small intestine, colon, blood, vagina, and rectum). The pH of wild-type griffithsin of SEQ ID NO: 2 is 5.1. internship daycareWebUS11339195B2 2024-05-24 Griffithsin mutants. US8394764B2 2013-03-12 Griffithsin, glycosylation-resistant griffithsin, and related conjugates, compositions, nucleic acids, … new directions internationalWebAug 2, 2011 · Many natural product-derived lectins such as the red algal lectin griffithsin (GRFT) have potent in vitro activity against viruses that display dense clusters of … internship dbb telkom