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Oxidized low-density lipoprotein receptor 1

Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) also known as lectin-type oxidized LDL receptor 1 (LOX-1) is a protein that in humans is encoded by the OLR1 gene. LOX-1 is the main receptor for oxidized LDL on endothelial cells, macrophages, smooth muscle cells, and other cell types. But minimally oxidized LDL is more … WebStudies have shown that oxidized low density lipoprotein (ox-LDL) elicits both necrotic and apoptotic cell death and several mechanisms have been proposed. ... Oxidized low …

OLR1 Gene - GeneCards OLR1 Protein OLR1 Antibody

WebAug 4, 1998 · LOX-1 is the major receptor for OxLDL expressed in vascular endothelial cells, presumably mediating the effects of OxLDL on endothelial cells. Sequencing showed that LOX-1 is a type II membrane protein that consists of 273 amino acids and belongs to the C-type lectin family. WebLOX-1 is one of the major receptors responsible for binding, internalizing, and degrading ox-LDL ( Li et al., 2000 ). LOX-1 has also been identified on monocytes/macrophages, … business drawings definition https://videotimesas.com

84-1929-11 LOX1 (LOX-1, hLOX-1, C-type Lectin Domain Family 8 …

WebNov 12, 2024 · Lox-1 (lectin-like oxLDL [oxidized low-density lipoprotein] receptor 1) signaling pathways. Lox-1 representation at the cell membrane, main downstream pathways triggered by activated Lox-1 and alterations in biological process and cell behaviors as … WebBackground: Hyperhomocysteinemia often results from vitamin deficiency and/or an unhealthy lifestyle. Because the condition is a risk factor for developing cerebrovascular disease or atherosclerosis, approaches that decrease plasma homocysteine level WebMar 21, 2024 · OLR1 (Oxidized Low Density Lipoprotein Receptor 1) is a Protein Coding gene. Diseases associated with OLR1 include Myocardial Infarction and Atherosclerosis … handshake video editor

ORIGINAL RESEARCH ARTICLE

Category:Oxidized Low Density Lipoprotein Receptor - ScienceDirect

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Oxidized low-density lipoprotein receptor 1

Lectin‐like oxidized low‐density lipoprotein receptor 1 pathways

WebNov 18, 2015 · The elevated level of low density lipoprotein (LDL) is generally considered to be the driver of atherosclerosis, but recent years have seen a shift in this perception in that the vascular... Web2.4.1 Lectin-Like Oxidized LDL Receptor 1 Lectin-like oxidized LDL receptor 1 (LOX-1), also called oxidized low-density lipoprotein receptor 1 (OLR1), is a major class E scavenger receptor for oxLDL, advanced glycation end products (AGEs), bacteria, and apoptotic cells ( Huysamen & Brown, 2009; Oka et al., 1998; Sawamura et al., 1997; Shimaoka ...

Oxidized low-density lipoprotein receptor 1

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WebLOX-1 is one of the major receptors responsible for binding, internalizing, and degrading ox-LDL ( Li et al., 2000 ). LOX-1 has also been identified on monocytes/macrophages, platelets, fibroblasts, neuron cells, and smooth muscle cells (SMCs) ( Ding et … WebApr 30, 2013 · Oxidized low-density lipoprotein (OxLDL) contributes to the atherosclerotic plaque formation and progression by several mechanisms, including the induction of endothelial cell activation and dysfunction, macrophage foam cell formation, and smooth muscle cell migration and proliferation.

WebSep 1, 2002 · Background: Lectin-like oxidized LDL receptor-I (LOX-1), a novel receptor for oxidized low-density lipoprotein, mediates oxidized low-density lipoprotein-induced … WebApr 10, 2024 · oxidized low density lipoprotein receptor 1 provided by HGNC Primary source HGNC:HGNC:8133 AllianceGenome:HGNC:8133 protein coding RefSeq status Organism Lineage Also known as LOX1; LOXIN; SLOX1; CLEC8A; SCARE1 Summary This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily.

WebDec 21, 2024 · Lactucopicrin at physiologically reachable concentrations inhibits oxidized low-density lipoprotein (oxLDL)-induced foam cell formation in inflammatory mouse bone marrow derived macrophages established by 50 pg mL –1 of LPS, reachable level in patients with metabolic endotoxemia. WebThe oxidized LDL receptor 1 (OLR1) gene encodes a receptor involved in endocytosis at the cell surface for oxidized LDL. In patients with a history of MI, Tatsuguchi et al. [22] found significantly higher frequency of the 501G > C (38.2%) compared to controls (17.6%). The OR for the risk of MI with the polymorphism was 2.89 [22].

WebOct 5, 2024 · Here, we clarified the exact role of autophagy modulated by the scavenger receptor lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in esophageal …

handshake virtual career fair demoWebOxLDL increases the oxLDL-dependent lectin-like oxidized low-density lipoprotein receptor-1 in endothelial cells, which causes an extension of ROS production. This process leads to apoptosis of endothelial cells and autophagy of granulosa cells [ 16 ]. handshake virtual eventsWebApr 14, 2024 · Ovarian aging hampers in vitro fertilization in assisted reproductive medicine and has no cure. Lipoprotein metabolism is associated with ovarian aging. It remains … business drawing ideas