The organic anion transporter oat family
Members of the Organo Anion Transporter (OAT) Family (organic-anion-transporting polypeptides, OATP) are membrane transport proteins or 'transporters' that mediate the transport of mainly organic anions across the cell membrane. Therefore, OATPs are present in the lipid bilayer of the cell membrane, acting as the cell's gatekeepers. OATPs belong to the Solute Carrier Family (SLC) and the major facilitator superfamily. WebbOrganic anion transporters play important roles in the elimination of a variety of endogenous substances, xenobiotics and their metabolites from the body. During the …
The organic anion transporter oat family
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WebbBxPC-3 and MIA PaCa-2 pancreatic cancer cell lines were used to quantify transcripts of OATP 1B1 and 1B3. Results: OATP 1A2, 1B1, and 1B3 proteins were found ubiquitously … WebbMentioning: 17 - The aim of this study was to explore whether rhein could enhance the effects of pemetrexed (PTX) on the therapy of non-small-cell lung cancer (NSCLC) and to clarify the associated molecular mechanism. Our study shows that rhein in combination with PTX could obviously increase the systemic exposure of PTX in rats, which would be …
WebbOATs are multispecific organic anion transporters, the substrates of which include both endogenous (e.g. cyclic nucleotides, prostaglandins, urate, dicarboxylates) and … WebbThe organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention …
Webb39 rader · 1 jan. 2015 · The organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 ... WebbThe organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention because of …
WebbThe organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention …
WebbOfficial Symbol : Slco3a1 Official Name : solute carrier organic anion transporter family, member 3a1 EnsemblGene ID : Other Names : Anr1, androgen regulated protein 1, solute … chipollinos handewittWebb1 aug. 2001 · The organic anion transporter (OAT) family handles a wide variety of clinically important compounds (antibiotics, nonsteriodal anti-inflammatory drugs, etc.) … chipolo black fridayWebbOrganic anion transporters (OATs) are shown in red, the organic cation/carnitine transporter (OCTN/CT) family is shown in blue, and organic cation transporters (OCTs) … grant thornton appletonWebb1 aug. 2001 · Abstract The organic anion transporter (OAT) family handles a wide variety of clinically important compounds (antibiotics, nonsteriodal anti-inflammatory drugs, … grant thornton applyWebb9 juni 2010 · The mycotoxin, ochratoxin A (OTA), is thought to be responsible for Balkan endemic nephropathy. OTA accumulates in several tissues, especially in the kidneys and … grant thornton application loginWebb10 maj 2024 · Organic anion transport. This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the … chipollworker.comWebbOrganic anion transporters (OATs) and organic cation transporters (OCTs) are members of the superfamily of transporters, Slc (solute carriers). Most are in the families Slc21 … grant thornton appraisal services