WebJun 18, 2015 · Background Epithelial-to-mesenchymal transition (EMT), which involves changes in cellular morphology of highly polarized epithelial cells and the gain of mesenchymal cell phenotype with migratory and invasive capacities, is implicated in smoking-related chronic obstructive pulmonary disease (COPD). However, the … WebRetired husband syndrome (主 人 在 宅ストレス症候群, Shujin Zaitaku Sutoresu Shoukougun, literally "One's Husband Being at Home Stress Syndrome")[1] (RHS) is a psychosomatic stress-related illness which has been estimated to occur in 60% of Japan's older female population.[2] It is a condition where a woman begins to exhibit signs of …
Tissue expression of TWIST2 - Summary - The Human Protein Atlas
WebJul 14, 2016 · Author Summary How muscle homeostasis is maintained is not completely elucidated yet. Epigenetic disorders such as Beckwith-Wiedemann syndrome, which causes hypergrowth of skeletal muscles and rhabdomyosarcoma, indicate that epigenetic regulations such as DNA methylation, contribute to this homeostasis control. DNA … WebNov 29, 2024 · Skeletal muscle repair and maintenance are directly and indirectly supported by interstitial cell populations such as vascular cells and fibro-adipogenic progenitors (FAPs), a subset of which express Twist2 and possess direct myogenic potential. Furthermore, work in rodents has highlighted the potential of pericytes to act as … the white knight\u0027s song
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WebTWIST2 (bHLHa39, Dermo-1, DERMO1) protein expression summary. Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MY OG, MEF2A and MEF2C. Also represses expression of pro-inflammatory cytokines such as TNFA and IL1B. WebApr 1, 2024 · Through the technique of lineage-tracing (fate-mapping) of the transcription factor Twist2, we have identified a novel muscle progenitor that fuses specifically to type IIb/x (fast-twitch, glycolytic) muscle fibers during both aging and homeostasis conditions. Additionally, loss of Twist2+ cells result in specific atrophy of fast-twitch myofibers. WebSkeletal muscle is maintained and repaired by sub-laminar, Pax7-expressing satellite cells. However, recent mouse investigations have described a second myogenic progenitor … the white knight wine